Two Stories of Disease: Smallpox and Polio

vaccination photo
Paul Lowry/Creative Commons

Smallpox plagued humanity for thousands of years. In the 18th century, smallpox killed one out of every ten children in France and Sweden. Over the 20th century, the virus caused between 300 and 500 million deaths worldwide. No effective treatment was ever developed. The eradication of this devastating disease is one of public health's greatest achievements. It involved mass vaccinations and surveillance to track and contain outbreaks. In 1977, ten years after the World Health Organization (WHO) began an intensive eradication program, the last naturally occurring case of smallpox was identified in Somalia. And on May 8, 1980, the World Health Assembly declared smallpox eradicated.

Graph on Global Smallpox Cases, 1920-2010

In 1988, when the WHO, Rotary International, the U.S. Centers for Disease Control, and UNICEF launched the Global Polio Eradication Initiative, it was hoped that vaccination and surveillance could also put an end to polio. Between 1988 and 2001, the number of cases of polio in the world fell from more than 300,000 to a low of 483, and success looked near.

 Graph on Wild Poliovirus Cases, 1985-2010

Since then, however, despite increasing expenditures and medical advancements, such as more effective vaccines, the number of recognized cases worldwide typically has exceeded 1,000.

 Graph on Wild Poliovirus Cases, 2000-2010

Once endemic to 125 countries, today polio transmission continues uninterrupted in only 4 countries: Afghanistan, India, Nigeria, and Pakistan; all but India are considered among the world's top failing states.

Failing states, those that lose control of part or all of their territory and can no longer ensure their people's security, can pose a threat to international health. They may lack a health care system that is sophisticated enough to participate in the international network that controls the spread of infectious diseases, as illustrated by recent missed opportunities to eradicate polio.

In 2003, mullahs in northern Nigeria began to oppose the polio vaccination program there, claiming that it was a plot to spread AIDS and sterility. As a result, the local vaccination effort broke down, and polio cases in Nigeria tripled over the next three years.

Graph on Wild Poliovirus Cases in Nigeria, 2000-2010

Meanwhile, Nigerian Muslims making their annual pilgrimage to Mecca may have spread the disease, reintroducing the virus in some Muslim countries, such as Indonesia, Chad, and Somalia, that were already polio-free. In response, Saudi officials imposed a polio vaccination requirement on all younger visitors from countries with reported cases of polio.

By February 2009, Nigerian state governors committed to ensure enough children would receive the polio vaccine to halt disease transmission. This dropped the number of cases nationally from nearly 400 in 2009 to 21 in 2010. As public attention turned from disease prevention to elections in the first half of 2011, the number of polio cases increased.

As in Nigeria, instability presents a significant obstacle to the eradication of polio in Pakistan. In early 2007, when eradication appeared to be in sight for the country, violent opposition to vaccinations arose in Pakistan's Northwest Frontier Province. In 2009, the Taliban refused to let health officials administer polio vaccinations in Pakistan's Swat Valley, further delaying the campaign. Then, the devastating floods in 2010 displaced millions, hindering vaccination initiatives and allowing the disease to spread.

This year Pakistan is on track for another rise in cases. At the end of August 2011, there have been 77 cases of polio in Pakistan, compared to the 43 cases for the same period in 2010. The Independent Monitoring Board of the Global Polio Eradication Initiative notes that "on its current course, Pakistan risks being the country that prevents global polio eradication."

Graph on Wild Poliovirus Cases in Pakistan, 2000-2010

Until polio is eradicated everywhere, it remains a concern for all countries. The spread of polio is just one way that the instability of failing states presents risks to the rest of the world. This raises a troubling question: In a world of failing states, is the goal of eradicating polio, once so close at hand, now beyond our reach?

Read more about disease:
Would You Vaccinate Your Kids?
Better Health For All: Critical To Reduce Population Growth & Poverty
Deadly Animal Disease Months from Extinction

Tags: Diseases

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