Breast Cancer Cell
We know, the Food and Drug Administration says Bisphenol A (BPA) is safe and the Government's role is to protect its citizens, not the chemical industry. Nevertheless, yet another study has just come out that shows the stuff lining our tin cans and polycarbonate bottles is a problem- it reduces the effectiveness of chemotherapy in breast cancer and possibly other kinds of cancer treatments.
BPA is structurally similar to estrogen; this creates the issue. The study's title says it all: "Bisphenol A at Low Nanomolar Doses Confers Chemoresistance in Estrogen Receptor Alpha Positive and Negative Breast Cancer Cells."
Our tipster Kate explains:
"BPA at environmentally relevant doses reduces the efficacy of chemotherapeutic agents. These data provide considerable support to the accumulating evidence that BPA is hazardous to human health.
In other words without using excessive doses of BPA protects both estrogen receptor positive and negative breast cancer tumors. The chemo drugs that were tested are doxorubicin, cisplatin and vinblastine.
Doxorubicin (Adriamycin/Rubex) is also used to treat bladder, head and neck, liver, lung, pancreatic and ovarian cancers as well as some leukemias and lymphomas.
Cisplatin (Platinol) is also used to treat testicular, ovarian and bladder cancers as well as Hodgkins and non Hodgkins lymphomas.
Vinblastine (Alkaban/Velban) is also used to treat lung, bladder, head and neck and other cancers as well as some Hodgkins and non Hodgkins lymphomas.
The research did not report on the effect of BPA on these chemotherapeutic agents with other cancer types."
Download a PDF of the tudy by Elizabeth W. LaPensee, Traci R. Tuttle, Sejal R. Fox, and Nira Ben-Jonathan, published October 8 in /11788.pdf">Environmental Health Perspectives
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